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Nanoparticle and Protein Sizing
Viscotek is proud to introduce its range of Dynamic Light Scattering Detectors featuring rapid, accurate and sensitive sizing for proteins, biomolecules, nanoparticles & polymers and a pair of outstanding technologies unique to Viscotek.
Conventional Calibration GPC System
RImaxTM Conventional Calibration System
RImax System
The Viscotek RImax is a robust Gel Permeation / Size Exclusion Chromatography system that is powerful yet easy to use. It represents the most reliable technology available for the conventional characterization of natural and synthetic polymers, copolymers, proteins, nanoparticles and other macromolecules. The RImax is configured as follows:
  • Model 3580 Refractive Index (RI) Detector with superior linearity and baseline stability.
  • GPCmax™ Integrated Pump/Autosampler/Degasser Module for automated solvent and sample delivery.
  • OmniSEC™ GPC/SEC software for data acquisition, processing and complete system control.
The Refractive Index (RI) Detector is known as the universal detector in GPC. It is used to measure sample concentration and determine dn/dc or refractive index increment. By adding a UV/VIS Detector to the RImax, concentration can be determined for those samples having a UV chromaphore. When employed in tandem, the RI and UV responses can be ratioed to determine copolymer composition.

Refractive Index Detector
RI Detector
The Viscotek Model 3580 Differential Refractive Index (RI) Detector sets the standard in GPC for the determination of sample concentration. It combines superior sensitivity and versatility with reliability, ease-of-use and excellent linearity over a wide range of concentrations. The Model 3580 mates seamlessly with the Viscotek GPCmax and OmniSEC software to form a complete Conventional GPC system. It can also be coupled with the Model 3210 UV/VIS for copolymer compositional analysis.

GPCmax
GPCmaxTM

The GPCmax is a unique, integrated pump, autosampler and degasser module specifically designed for GPC/SEC applications. It features a variable injection volume autosampler capable of handling 2 ml or 20 ml vials, an isocratic pump for pulseless and reproducible solvent flow and an in-line solvent degasser. The GPCmax is controlled by the OmniSEC software and mates seamlessly with the Model 3580 Refractive Index (RI) Detector to form a complete GPC/SEC system.


OmniSEC™ Software
OmniSEC Software
OmniSEC is a powerful and flexible GPC/SEC software program specifically designed to maximize the information content and efficiency of the gel permeation chromatography (GPC) experiment. Key features include interactive programs for calculation of results in a real-time time environment, automatic baseline and peak detection, multiple peak analysis, copolymer and conjugate compositional analysis and determination of A2 and B22 values. OmniSEC allows full control of the RImax GPC/SEC system along with data acquisition, processing and export, and is 21 CFR part 11 compliant.

For more information, including full technical specifications, performance information and product details, please click below to download our product brochure.

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Complete Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) systems for the characterization of natural and synthetic polymers, proteins, conjugates and excipients. Integrated Triple and Tetra Detector Arrays (TDAs) featuring Low Angle Light Scattering (LALS) detectors, four capillary differential viscometer detectors, refractometers and UV/VIS detectors; in a single experiment, obtain absolute molecular weight, molecular size, intrinsic viscosity, conformation, polymer branching, aggregation, and copolymer characterization. Flow Injection Polymer Analysis (FIPA) for fast, accurate and precise average molecular weight, size and intrinsic viscosity in routine QA/QC and process control. Automated Dilute Solution Viscosity (DSV) systems provide relative, inherent, and intrinsic viscosity.